Rank | Weekend Total | Weeks | Screens | Weekend screen avg. | Cumulative box office |
|---|
| 1. | G.I. Joe: Rise of Cobra (2009)  |
$54,713,046 (%) | 1 | 4,007 | $13,654 | $54,713,046 |
| 2. | Julie & Julia (2009)  |
$20,027,956 (%) | 1 | 2,354 | $8,508 | $20,027,956 |
| 3. | G-Force (2009)  |
$9,870,594 (-44%) | 3 | 3,482 | $2,834 | $86,183,076 |
| 4. | Harry Potter and the Half-Blood Prince (2009)  |
$8,928,349 (-50%) | 4 | 3,455 | $2,584 | $273,848,633 |
| 5. | Funny People (2009)  |
$7,986,435 (-65%) | 2 | 3,008 | $2,655 | $40,537,755 |
| 6. | The Ugly Truth (2009)  |
$6,750,125 (-49%) | 3 | 2,975 | $2,268 | $68,838,257 |
| 7. | A Perfect Getaway (2009)  |
$5,948,555 (%) | 1 | 2,159 | $2,755 | $5,948,555 |
| 8. | Aliens In the Attic (2009)  |
$4,021,478 (-50%) | 2 | 3,108 | $1,293 | $16,314,371 |
| 9. | 500 Days of Summer (2009)  |
$3,739,702 (35%) | 4 | 817 | $4,577 | $12,357,265 |
| 10. | Orphan (2009)  |
$3,674,306 (-51%) | 3 | 2,270 | $1,618 | $34,766,199 |